Job Description

Role: Scientist \xe2\x80\x93 Physical Chemistry, Permanent

Salary: \xc2\xa330,000 plus excellent benefits

Hours: Full time, 37.5 hours per week

Location: , Macclesfield, SK10 4TG.

Our Company

Cyprotex vision is to be pioneers of innovative ADME-Tox partnerships, driving delivery of safer and more effective medicines. With state-of-the-art facilities and technical expertise, we specialise in in vitro and in silico ADME-Tox services, providing a wide range of assays tailored to our client\xe2\x80\x99s needs. This includes in vitro screening to support discovery projects, regulatory studies to support preclinical and clinical development, specialist mechanistic in vitro human and animal toxicity models and PBPK/QSAR modelling expertise. As well as supporting clients directly, we have a strong focus on R&D.

Our Alderley Park site is set in the heart of Cheshire surrounded by stunning 400-acre estate, open green spaces, sweeping viewpoints, all within easy reach of Merseyside and Greater Manchester, Staffordshire, and Shropshire. Easy access to public transport.

As a result of year-on-year success within the company and continued business growth, exciting opportunities have arisen to join our team of 30+ drug metabolism scientists. We are responsible for delivering high quality metabolic stability, enzyme inhibition, enzyme kinetics and enzyme induction data to our clients, supporting projects from early discovery right through to clinical development. As a member of the team, you will develop in depth technical expertise across all these areas and understand how this data is utilised to support drug discovery and inform clinical development.

The Role as our Scientist

As a Scientist you will be primarily laboratory-based, working with our highly skilled team to ensure that Physical Chemistry assays, both commercial and R&D focussed, are performed to a high standard and within scheduled timeframes. In addition, you will support the training and development of staff, improving the team\xe2\x80\x99s knowledge and processes.

Key Responsibilities

• To conduct both routine and bespoke Physical Chemistry assays (both manually and using liquid-handling robots).
• To coach and mentor more junior scientists and other colleagues within the team on assay execution and data analysis.
• To demonstrate ability to use scientific knowledge in data analysis, interpretation and troubleshooting.
• To be responsible for management of assigned assays, take ownership for the planning and delivery of these assays, communicating effectively with team members and the study managers.
• To support senior team members with assay development and validation and design of bespoke assays.
• To ensure that all errors and erroneous results are reported to your supervisor with minimal delay.
• To keep up to date with relevant scientific advances and regulatory guidelines in the field of Physical Chemistry.
• To monitor and maintain stock consumables, communicating with internal buyers and external suppliers.
• To ensure accurate and complete documentation of all activities as required by relevant SOPs and Quality policies.
• To ensure work is performed to an exceptionally high standard, within specified time frames, ensuring safety regulations and QC procedures are strictly adhered to.

Education, Qualifications and Experience

• Significant experience working within a laboratory environment is essential. Practical experience in conducting Physical Chemistry measurements aligned to understanding ADMET is advantageous.
• BSc/MSc, or higher, in Chemistry, Drug Metabolism or a related field.
• Knowledge of general laboratory processes is essential and experience in any of the following is advantageous: liquid handling robotics (such as Tecan EVO\xc2\xae platform), UPLC-UV-MS/MS and subsequent data analysis.
• Strong communication and time-management skills to organise and deliver high-quality data in a fast-paced environment.

What we can offer you in return

We offer a competitive salary and benefits package.

• Company Pension Scheme.
• 25 days holiday plus bank holidays and additional length of service days awarded on the anniversary, up to a maximum of 30 days.
• Private health insurance with BUPA for the employee and their partner/family under the company scheme
• Wellbeing support 24/7 and counselling services
• Permanent health insurance provides 75% of the base salary after the qualifying period.
• Private dental cover, on completion (but not subject to) of your 3-month probationary period
• Eligibility to participate in the Company Bonus Scheme. This is a discretionary benefit.
• Career progression within the company, we have excellent training and support and continuing professional development opportunities.
• Cycle-to-work scheme
• Refer a friend scheme, team and annual events, recognition awards and many more.

Onsite Facilities

• The company pays for secure onsite parking.
• Restaurant, caf\xc3\xa9, and a gastro pub
• Gym and workout studio, running, walking, and cycling routes.
• Good public transport links with the shuttle bus service.

Interested?

Apply NOW \xe2\x80\x93 please upload your up-to-date CV and cover letter to Workday via our careers page.

FR : Dans le cadre de sa politique Diversit\xc3\xa9, Evotec \xc3\xa9tudie, \xc3\xa0 comp\xc3\xa9tences \xc3\xa9gales, toutes les candidatures dont celles des personnes en situation de handicap.

ENG : In the frame of our Diversity policy, Evotec considers, with equal competences, all applications including people with disabilities.

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