Job Description

The Kennedy Institute has an exciting opening for a highly motivated post-doc to join the groups of Professor Fiona Powrie (https://www.kennedy.ox.ac.uk/research/mucosal-immunology) and Associate Professor Stephen Sansom (https://sansomlab.org). We are looking for a talented individual to lead bioinformatic investigations of inflammatory bowel disease and colorectal cancer. In this role you will work closely with wet-lab and clinical colleagues in a world-class interdisciplinary project team at the University of Oxford. Your research will take advantage of rich datasets from large-scale patient cohorts, single-cell experiments and our cutting-edge spatial transcriptomics platforms. Novel findings will be prioritised and mechanistically tested in close partnership with wet-lab colleagues. There will be opportunity to develop novel computational methods and to help translate discoveries into the clinic with our clinical collaborators at the Translational Gastroenterology Unit in Oxford and the Cambridge Institute of Therapeutic Immunology and Infectious Disease.

You should be able to demonstrate a passion and desire to conduct investigative research that is aligned with the project goals. You will have expert knowledge of cellular biology, experience with statistical analysis and hands-on experience with analysing genomic/transcriptomic datasets with Python and/or R. You should have a track record of writing scientific papers as evidenced by publications or submitted manuscripts in peer-reviewed journals. A PhD/DPhil in a discipline of direct relevance to computational genomics and/or cellular immunology research is essential. In this role, you will perform scientific research, reviewing and refining working hypotheses and developing and acquiring relevant skills as necessary. You will analyse and interpret data, preparing and publishing your findings in peer-reviewed journals. You will help to train and supervise graduate and undergraduate students as appropriate . The successful applicant will be based at the Kennedy Institute of Rheumatology within the Nuffield Department of Orthopaedics, Rheumatology and Musculoskeletal Sciences.

Recent PhD/DPhil graduates and candidates originally from experimental backgrounds wishing to aquire further training in computational research are strongly encouraged to apply if they can demonstrate a strong aptitude for computer programming and statistical data analysis.

Please read the accompanying job description carefully and ensure that you address each selection criteria in a supporting statement which must be uploaded together with your CV when applying online.

For further information please contact Dr Stephen Sansom: stephen.sansom@kennedy.ox.ac.uk and/or Prof Fiona Powrie: fiona.powrie@kennedy.ox.ac.uk

This is a fixed-term, full time position for 3 years.

Due to the nature of the research at the Kennedy Institute of Rheumatology, this job will require additional security pre-employment checks:

• A satisfactory basic Disclosure and Barring Service check

A lower grade offer (Grade 7: \xc2\xa336024- \xc2\xa3 44263p.a.) may be made to a less experienced candidate (such as recent PhD/DPhil graduates) or candidates originally from experimental backgrounds who need further training in computational research if a suitable candidate cannot be found to fill the Grade 8 position.

\xc2\xa345,585 to \xc2\xa354,395 per annum : Grade 8

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