At the Reference Services Division - Colindale (RSDC) laboratory teams undertake services of complex and highly skilled techniques which often require nationally or internationally unique capabilities or facilities. RSDC are required to provide authoritative, final and validated analysis for complex clinical or food microbiological/virological problems and be innovative in driving microbiological/virological methodology developments and standards. They have a key role in provision of expert advice to government, national and international agencies, risk assessment for new and emerging microbiological/virological threats and play an important role in teaching and training organism specific and subject matter expertise to all grades of professional medical, nursing, scientific and technical staff. Design of national microbiological/virological surveillance programmes and sampling strategies and outbreak detection and control are part of day to day work of reference laboratories.
The Antimicrobial Resistance and Healthcare Associated Infections (AMRHAI) Reference Unit is the national reference laboratory for investigation of antibiotic resistance in, and characterization of, healthcare associated pathogens. We seek to define outbreaks and identify transmission pathways. We use established and developmental phenotypic and genotypic methods to type isolates, to identify markers of virulence, fitness and epidemicity, and to determine their susceptibility to relevant antibiotics. Likely mechanisms of antimicrobial resistance are inferred by interpretive reading, and we offer molecular detection and confirmation of the genetic determinants of key resistances and monitor their dissemination. AMRHAI undertakes surveillance of resistance, advises on outbreak investigation, antimicrobial agents that may be appropriate for therapy, and on any public health risk. It is also the national reference laboratory for pathogens from patients with cystic fibrosis (CF).
In addition, we provide specialist identification services for 'unknowns', which includes atypical, difficult to isolate or emerging bacterial pathogens detected in culture-negative clinical samples and for isolates with no national reference facility.
We pride ourselves as being an employer of choice, where Everyone Matters promoting equality of opportunity to actively encourage applications from everyone, including groups currently underrepresented in our workforce.
UKHSA ethos is to be an inclusive organisation for all our staff and stakeholders. To create, nurture and sustain an inclusive culture, where differences drive innovative solutions to meet the needs of our workforce and wider communities. We do this through celebrating and protecting differences by removing barriers and promoting equity and equality of opportunity for all.
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