Job Information Organisation/Company
UK Dementia Research Institute Research Field
Other Researcher Profile
First Stage Researcher (R1) Country
United Kingdom Application Deadline
22 Feb 2024 - 17:00 (Europe/London) Type of Contract
Temporary Job Status
Full-time Hours Per Week
37.5 Offer Starting Date
1 Apr 2024 Is the job funded through the EU Research Framework Programme?
Not funded by an EU programme Reference Number
B02-06467 Is the Job related to staff position within a Research Infrastructure?
No
Offer Description
Dementia is the biggest health challenge of our century - currently affecting fifty million people worldwide, projected to triple by 2050, with huge financial, emotional and social impact on people directly affected, their carers, families and the community.
Dementia is a symptom of several neurodegenerative disorders, with Alzheimer\'s disease accounting for about 60% of cases. To date there is no way to prevent or even slow the rate of progression of neurodegeneration - there is still a major knowledge gap in our basic understanding of the diseases.
The UK Dementia Research Institute (UK DRI) is the biggest UK initiative supporting research to fill this gap.
We are a globally leading multidisciplinary research institute of over 700 staff investigating the spectrum of neurodegenerative disorders causing dementia, driving a step change in our understanding of neurodegeneration and accelerating the discovery, development and delivery of interventions that will help diagnose, treat and ultimately prevent dementia. Our laboratory-based research groups and associated support staff are located within and employed by University College London, the University of Cambridge, Cardiff University, Edinburgh University, Imperial College London and King\'s College London.
UK DRI core data science team
Neurodegenerative research spans various scales, from molecular to population levels and it benefits immensely from the rapidly evolving innovations in informatics and data science and the growing collation of omics and population level life-course data. The UK DRI holds the lead in identifying novel questions that can only be addressed with the inclusion of such innovations. The UK DRI data science team will serve as the core for the UK DRI national informatics programme over the next four years. The team will enhance data access, training, partnerships, and technical capacity for researchers, fostering data sharing and boosting data science capabilities. The team is currently based at UCL and interacts closely with the UK DRI UCL centre staff.
About the role
UK DRI researchers are currently generating a large amount of data ranging from omics data, including spatial transcriptomics, and imaging, to video recordings. The growth of the data necessitates standardised processes for systemic data integration while ensuring data quality is not compromised.
We have an exciting opportunity to join our newly founded informatics team as a bioinformatician. You will be committed to tackling dementia through collaborative efforts across an organisation that is committed to advancing dementia research.
As a bioinformatician, you will develop, maintain, and run data analysis pipeline infrastructure established by the data science team. You will also participate in several stages of data lifecycle management such as data processing, curation, management, and submission of the large and diverse amounts of data generated by UK DRI research teams.
You will interrogate and resolve potential issues associated with the data sets. As an active member in the research projects that you will engage with, you will take part in developing approaches for safeguarding high data quality and ensuring that key people are kept informed of the progress. You will work together with other UK DRI software developers and bioinformaticians to standardise and troubleshoot reporting and processes.
The post is available immediately and funded by UK DRI until 31 March 2028 in the first instance.
This role is eligible for hybrid working with a minimum of 20% of time on site.
Requirements
Research Field Other Education Level PhD or equivalent
Skills/Qualifications
You will be interested in the research and mission of the UK DRI, enthusiastic about joining our newly established data science team, and passionate about working effectively and collaboratively with researchers at all levels across the Institute.
You will hold a PhD or equivalent in a relevant scientific discipline or have equivalent practical experience working in the biomedical or health informatics domain. You will have experience in informatics techniques, data management, and data curation, as well as a good understanding of workflow management tools like Nextflow and Snakemake. In addition, you will have experience in programming (R, Python, etc.) and in agile software development processes and management using GitHub.
This role meets the eligibility requirements for a skilled worker certificate of sponsorship or a global talent visa under UK Visas and Immigration legislation. Therefore, UCL welcomes applications from international applicants who require a visa.
Informal enquiries regarding the role can be addressed to Amonida Zadissa, Associate Director of Informatics ( ).
Additional Information
Benefits
Appointment at Grade 7 is dependent upon having been awarded a PhD; if this is not the case, initial appointment will be at research assistant Grade 6B (salary \xc2\xa337,332 - \xc2\xa339,980 per annum) with payment at Grade 7 being backdated to the date of final submission of the PhD thesis.
As well as the exciting opportunities this role presents, we also offer great benefits, some of which are below:
EURAXESS
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