Job Description

Adaptimmune is a clinical-stage biopharmaceutical company focused on the development and commercialization of novel immunotherapy products for people with cancer. The Company\'s unique SPEAR (Specific Peptide Enhanced Affinity Receptor) T-cell platform enables the engineering of T-cells to target and destroy cancer across multiple solid tumors.

Our company culture is rooted in trust, inclusion, our capacity to collaborate, and our commitment to being honest and brave in our desire to successfully transform the lives of people with cancer.

Adaptimmune\xe2\x80\x99s Off-the-Shelf T cell project is focused on the development of an iPSC derived T-cell product. The project team is growing rapidly to enable delivery of a ground-breaking new therapy and ensure the company\xe2\x80\x99s position as a leader in the allogeneic cell therapy field. We seek a talented and motivated individual with expertise in cell and molecular biology to join the expanding gene editing team.

Reporting to the Group Leader, individual will be responsible for performing transgene knock-in /gene inactivation, isolation and genotyping of single cell clones, molecular characterisation, next-generation sequencing (NGS), and construct cloning. The postholder will also perform cell culture of induced pluripotent stem cells (iPSC) to support Adaptimmune\xe2\x80\x99s gene editing pipeline.

Key Responsibilities

• Cell culture of iPSC line for genome editing
• Support projects through molecular biology techniques, including PCR, cloning, and sequencing
• Design and conduct experiments to ensure robust and meaningful data generation
• Plan and execute experimental work
• Record and analyse experimental results
• Maintain relevant databases and records
• Analyse, summarise and record experimental results in electronic lab notebooks and slide preparation
• Participate in group and project meetings and discussions.
• Contribute to routine lab maintenance

Qualifications & Experience

• Degree/MSc in Lifesciences or related discipline
• Relevant experience of molecular biology and cell biology
• Experience with molecular biology techniques eg. PCR (ddPCR, dPCR, qPCR), cloning, plasmid DNA purification
• Ability to work independently on routine experiments
• Ability to learn and develop in order to work independently on non-routine experiments within a reasonable time frame
• Aseptic cell culture experience
• Enthusiasm for technical challenges

Desirable

• Relevant post-graduate experience, possibly including an MSc or PhD in a relevant scientific area.
• An understanding of gene editing including CRISPR-Cas9
• Relevant laboratory experience in either biotech or pharma industry

At Adaptimmune we embrace diversity and equality of opportunity. We believe that the more inclusive we are, the better our work will be. We welcome applications to join our team from all qualified candidates, regardless of age, colour, disability, marital status, national origin, race, religion, gender, sexual orientation, gender identity, veteran status or other legally protected category. It is our intent that all qualified applicants will receive equal consideration for employment.

Apply

Apply for this position

Required*

Apply with

First Name*

Last Name*

Email Address*

Phone*

Address*

Resume*

We\'ve received your resume. Click to update it.

or

Attach resume as .pdf, .doc, .docx, .odt, .txt, or .rtf (limit 5MB) or

Paste your resume here or

At Adaptimmune we embrace diversity and equality of opportunity. We believe the more inclusive we are, the better our work will be. We welcome applications to join our team from all qualified candidates, regardless of age, race, religion, sex, national origin, disability, pregnancy, genetic information, VISA status, sexual orientation, gender identity or other characteristics protected under law. Providing this information will help us measure effectiveness and progress of our talent attraction, sourcing and recruitment strategies and will only be used for these legitimate purposes. Submission of this information is voluntary and refusal to provide it will not result in any adverse treatment.

PLEASE PROVIDE AN ANSWER TO THE FOLLOWING:

WHAT IS YOUR RACE?*

By continuing with and submitting your application, you are agreeing to the following:

1. You have read and understood the statements made in the consent form and the ways in which your personal data will be stored and processed.
2. To the storing and processing of your personal information by Adaptimmune, members of the Adaptimmune group of companies and third parties working on behalf of Adaptimmune as set out in the consent form.
3. To the storing and processing of your personal information outside of the European Union and to the transfer of personal information between the EU and the United States.
4. To the storing of personal information for the periods set out in the Privacy Notice.
5. You understand that you can withdraw your consent at any time. **

Do you have the independent right to live and work in this country without the need for Visa sponsorship? **

At Adaptimmune we embrace diversity and equality of opportunity. We believe the more inclusive we are, the better our work will be. We welcome applications to join our team from all qualified candidates, regardless of age, race, religion, sex, national origin, disability, pregnancy, genetic information, VISA status, sexual orientation, gender identity or other characteristics protected under law. Providing this information will help us measure effectiveness and progress of our talent attraction, sourcing and recruitment strategies and will only be used for these legitimate purposes. Submission of this information is voluntary and refusal to provide it will not result in any adverse treatment.

Adaptimmune